Do you know how the wound healed? Do you know what your body experienced during the rehabilitation process?
The nerve cells in our skin help the wound to heal. When we get injured, a glial cell becomes a repair cell that spreads into the wound area to help the skin heal.
An important step in the process of skin wound healing is wound closure, which is why blood clotting occurs at the wound shortly after the injury occurs. However, if you want to ensure that the injury can be permanently healed, the body needs to re-form the affected skin layer. The longer the injury, the longer the recovery time. The older you are, the weaker the recovery ability is. During the long recovery period, there is a magical, complex, and partially understood interaction between the various cells in our skin. With the in-depth study of medical researchers, it has now been demonstrated that peripheral nerve cells play a central role in this healing process.
Glial cells change their identity
Signs of long-term research show that in order for wounds to heal optimally, tissues need to be innervated by the supply. However, the current reason is not yet clear. With the help of an animal model, the researchers found that fine nerve bundles can change drastically when skin trauma occurs. Glial cells (cells along damaged bundles of nerves) change their original identity and reprogram them as “repair cells.” As a result, they lose contact with the nerve bundles and are unable to spread to the wound bed. Through genetic experiments it can be shown that, among other things, these repair cells are very important for helping wounds because they support the necessary reconstruction of the dermis.
There is also a condition called chronic wound healing.
For example, slow healing of wounds often occurs in elderly or diabetic patients, sometimes even with non-healing conditions. This chronic wound usually leads to serious health problems, but the current treatment is not ideal.